The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 12, 2019

Filed:

May. 04, 2016
Applicant:

The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);

Inventors:

John Michael Ramsey, Chapel Hill, NC (US);

Laurent D. Menard, Raleigh, NC (US);

Michael A. Tycon, San Jose, CA (US);

Oscar A. McCrate, Carrboro, NC (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G01N 15/14 (2006.01); G01N 15/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502761 (2013.01); G01N 15/1463 (2013.01); G01N 15/1484 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/0896 (2013.01); B01L 2400/0421 (2013.01); G01N 15/1459 (2013.01); G01N 2015/0038 (2013.01);
Abstract

Fluidic devices with a primary transport nanochannel(s) intersected by at least one nanoscale manifold for active control of capture, manipulation and transport of analyte molecules. The at least one manifold can be an array or network of nanochannels, nanoslits or nanoelectrodes joined to a common voltage or pressure source. A respective nanoscale manifold can be configured to allow for precise and active control of driving forces applied to the primary transport nanochannel(s) to drive molecular transport through the various regions along the transport nanochannel(s). The at least one manifold can generate monotonic force gradients with a limited or reduced number of independent input potentials and/or pressures applied to the device.


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