The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 12, 2019
Filed:
Jun. 08, 2017
University of Cincinnati, Cincinnati, OH (US);
Eccrine Systems, Inc., West Chester, OH (US);
Jason Charles Heikenfeld, Cincinnati, OH (US);
Andrew Jajack, Cincinnati, OH (US);
Michael Charles Brothers, Covington, KY (US);
University of Cincinnati, Cincinnati, OH (US);
Abstract
A device for increasing a concentration of at least one analyte in an advective flow of biofluid includes an agent for enhancing a paracellular permeability of an epithelial tissue; and an iontophoresis electrode and a counter electrode, which are adapted to increase the concentration of said analyte in the advective flow of the biofluid. A method of sensing an analyte in a biofluid includes increasing a paracellular permeability of an epithelial tissue layer; and inducing electro-osmotic flow by reverse iontophoresis to increase a concentration of said analyte in an advective flow of the biofluid, wherein said advective flow is driven by at least one of saliva generation, sweat generation, or reverse iontophoresis.