The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 12, 2019

Filed:

Dec. 12, 2016
Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventors:

Fabiana Kimie Kashiwabuchi, Baltimore, MD (US);

Justin Hanes, Baltimore, MD (US);

Hai-Quan Mao, Baltimore, MD (US);

Peter John McDonnell, Baltimore, MD (US);

Qingguo Xu, Baltimore, MD (US);

Shuming Zhang, Baltimore, MD (US);

Kunal S. Parikh, Reynoldsburg, OH (US);

Assignee:

The Johns Hopkins University, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
D01D 5/04 (2006.01); D01D 5/06 (2006.01); D01D 10/06 (2006.01); A61L 17/00 (2006.01); B29C 48/00 (2019.01); B29C 48/14 (2019.01); D01D 5/00 (2006.01); D02G 3/44 (2006.01); A61K 31/5383 (2006.01); B29K 67/00 (2006.01); B29K 105/00 (2006.01); B29L 31/00 (2006.01);
U.S. Cl.
CPC ...
A61L 17/005 (2013.01); A61K 31/5383 (2013.01); B29C 48/022 (2019.02); B29C 48/142 (2019.02); B29C 48/147 (2019.02); D01D 5/0007 (2013.01); D01D 5/0038 (2013.01); D01D 5/0046 (2013.01); D01D 5/0076 (2013.01); D02G 3/448 (2013.01); A61L 2300/604 (2013.01); A61L 2430/16 (2013.01); B29K 2067/046 (2013.01); B29K 2105/0035 (2013.01); B29K 2995/006 (2013.01); B29K 2995/0056 (2013.01); B29L 2031/7546 (2013.01);
Abstract

Ophthalmic suture materials made from biocompatible and biodegradable polymers with high tensile strength for use in drug delivery, methods of making them, and method of using them for ocular surgery and repair have been developed. The suture materials are made from a combination of a biodegradable, biocompatible polymer and a hydrophilic biocompatible polymer. In a preferred embodiment the suture materials are made from a poly(hydroxyl acid) such as poly(1-lactic acid) and a polyalkylene oxide such as poly(ethylene glycol) or a polyalkylene oxide block copolymer. The sutures entrap (e.g., encapsulate) one or more therapeutic, prophylactic or diagnostic agents and provide prolonged release over a period of at least a week, preferably a month.


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