The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 12, 2019

Filed:

Aug. 05, 2014
Applicant:

Nof Corporation, Tokyo, JP;

Inventors:

Shunsuke Sakurai, Kawasaki, JP;

Koji Miyamoto, Kawasaki, JP;

Yohei Takada, Kawasaki, JP;

Yoshihisa Shimamura, Kawasaki, JP;

Mao Maruhashi, Kawasaki, JP;

Nobuyuki Sakamoto, Kawasaki, JP;

Assignee:

NOF Corporation, Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 31/155 (2006.01); A61K 47/02 (2006.01); A61K 47/32 (2006.01); A61K 47/38 (2006.01); A61L 12/14 (2006.01); A61L 12/10 (2006.01); A61K 47/34 (2017.01);
U.S. Cl.
CPC ...
A61L 12/10 (2013.01); A61K 9/0048 (2013.01); A61K 31/155 (2013.01); A61K 47/02 (2013.01); A61K 47/32 (2013.01); A61K 47/34 (2013.01); A61K 47/38 (2013.01); A61L 12/14 (2013.01); A61L 12/141 (2013.01); A61L 12/142 (2013.01);
Abstract

Provided is an ophthalmic solution of which preservative component, hexamethylene biguanide, contained therein is inhibited from being adsorbed on soft contact lenses and eye droppers. The ophthalmic solution contains, at a specific ratio, (A) hydroxypropyl methylcellulose having 28.0 to 30.0 mass % methoxy groups and 7.0 to 12.0 mass % hydroxypropoxy groups, both with respect to the total amount of the hydroxypropyl methylcellulose, at a methoxy group/hydroxypropoxy group ratio of 2.5 to 4.0 by mass, wherein a 2 mass % aqueous solution of the hydroxypropyl methylcellulose at 20° C. has a viscosity of 50 to 4000 mPa·s; (B) sodium chloride or potassium chloride; (C) hexamethylene biguanide or a salt thereof; (D) 2-methacryloyloxyethyl phosphorylcholine/butyl methacrylate copolymer; and (E) water.


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