The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 12, 2019
Filed:
Aug. 08, 2016
Applicant:
Fei Xiao, Beijing, CN;
Inventors:
Jie Ma, Beijing, CN;
Fei Xiao, Beijing, CN;
Hongjun Ren, Beijing, CN;
Wei Wang, Beijing, CN;
Hongtao Xu, Beijing, CN;
Meng Wang, Beijing, CN;
Lihui Zou, Beijing, CN;
Fei Ding, Beijing, CN;
Fei Su, Beijing, CN;
Assignee:
Other;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/10 (2006.01); A61K 47/60 (2017.01); A61K 31/407 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/60 (2017.08); A61K 31/407 (2013.01); A61P 35/00 (2018.01); C07D 487/10 (2013.01);
Abstract
The present invention relates to a spirocyclic indolone polyethylene glycol carbonate compound, a composition thereof, a preparation method therefor, and a use thereof as an anticancer drug due to the antitumor activity thereof. The structural formula of the spirocyclic indolone polyethylene glycol carbonate compound is shown below. The compound has excellent tumor inhibitory activity, water solubility, low toxicity, and can be used for intravenous injection.