The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 12, 2019
Filed:
Apr. 27, 2015
Applicants:
Genethon, Evry, FR;
International Centre for Genetic Engineering and Biotechnology, Trieste, IT;
Inventors:
Federico Mingozzi, Paris, FR;
Giuseppe Ronzitti, Paris, FR;
Fanny Collaud, Paris, FR;
Andrés Muro, Trieste, IT;
Giulia Bortolussi, Travesio, IT;
Assignees:
GENETHON, Evry, FR;
INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY, Trieste, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/45 (2006.01); C12N 15/86 (2006.01); A61K 48/00 (2006.01); C12N 9/10 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/45 (2013.01); A61K 48/0058 (2013.01); A61K 48/0066 (2013.01); C12N 7/00 (2013.01); C12N 9/1051 (2013.01); C12N 15/86 (2013.01); C12Y 204/01017 (2013.01); C12N 2750/14143 (2013.01); C12N 2830/008 (2013.01); C12N 2830/42 (2013.01);
Abstract
The invention relates to a nucleic acid sequence useful in the treatment of hyperbilirubinemia, in particular in the treatment of Crigler-Najjar syndrome. More particularly, the nucleic acid sequence of the present invention is a codon-optimized UGT1A1 coding sequence.