The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 12, 2019

Filed:

Jun. 05, 2017
Applicant:

Verona Pharma Plc, Cardiff, GB;

Inventors:

Michael J. A. Walker, Vancouver, CA;

Mario Cazzola, Naples, IT;

Luigino Calzetta, Rome, IT;

Assignee:

Verona Pharma PLC, Cardiff, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 31/40 (2006.01); A61K 45/06 (2006.01); A61K 9/00 (2006.01); A61K 31/137 (2006.01); A61K 31/167 (2006.01); A61K 31/44 (2006.01); A61K 31/46 (2006.01); A61K 9/48 (2006.01); A61M 15/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 9/008 (2013.01); A61K 9/0075 (2013.01); A61K 9/0078 (2013.01); A61K 9/0095 (2013.01); A61K 9/4858 (2013.01); A61K 31/137 (2013.01); A61K 31/167 (2013.01); A61K 31/40 (2013.01); A61K 31/44 (2013.01); A61K 31/46 (2013.01); A61K 45/06 (2013.01); A61M 15/009 (2013.01); A61M 2202/064 (2013.01);
Abstract

The invention provides a composition which comprises (a) a PDE3/PDE4 inhibitor which is 9,10-Dimethoxy-2-(2,4,6-trimethylphenylimino)-3-(N-carbamoyl-2-aminoethyl)-3,4,6,7-tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-one or a pharmaceutically acceptable acid addition salt thereof and (b) a muscarinic receptor antagonist.


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