The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 12, 2019

Filed:

Oct. 05, 2018
Applicants:

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);

University of Utah Research Foundation, Salt Lake City, UT (US);

Inventors:

Matthew B. Boxer, Frederick, MD (US);

Martin J. Walsh, Carmel, IN (US);

Li Liu, Germantown, MD (US);

Cordelle D. Tanega, Rockville, MD (US);

Min Shen, Boyds, MD (US);

Kent Lai, Salt Lake City, UT (US);

Manshu Tang, Salt Lake City, UT (US);

Douglas S. Auld, Beverly, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01); A61K 31/517 (2006.01); A61K 31/506 (2006.01); C07D 413/14 (2006.01); C07D 413/12 (2006.01); C07D 493/10 (2006.01); C07D 495/10 (2006.01); C07D 417/14 (2006.01); C07D 491/107 (2006.01); A61K 31/527 (2006.01);
U.S. Cl.
CPC ...
A61K 31/517 (2013.01); A61K 31/506 (2013.01); A61K 31/527 (2013.01); C07D 403/12 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 491/107 (2013.01); C07D 493/10 (2013.01); C07D 495/10 (2013.01);
Abstract

Disclosed are inhibitors of human galactokinase of formula (I) that are useful in treating or preventing a galactokinase mediated disease or disorder, e.g., galactosemia. Also disclosed are a composition comprising a pharmaceutically acceptable carrier and at least one inhibitor of the invention, and a method of treating or preventing such disease or disorder in a mammal. Formula (I).


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