The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 12, 2019

Filed:

May. 26, 2015
Applicants:

The Regents of the University of California, Oakland, CA (US);

The Trustees of the University of Pennsylvania, Philadelphia, PA (US);

Inventors:

Danny J J Wang, Oak Park, CA (US);

Lirong Yan, Los Angeles, CA (US);

Hee Kwon Song, Moorestown, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01R 33/48 (2006.01); A61B 5/026 (2006.01); G01R 33/563 (2006.01); A61B 5/055 (2006.01); G01R 33/56 (2006.01); G01R 33/561 (2006.01);
U.S. Cl.
CPC ...
A61B 5/0263 (2013.01); A61B 5/055 (2013.01); G01R 33/4806 (2013.01); G01R 33/4818 (2013.01); G01R 33/4828 (2013.01); G01R 33/5635 (2013.01); G01R 33/56333 (2013.01); G01R 33/4824 (2013.01); G01R 33/5601 (2013.01); G01R 33/5611 (2013.01); G01R 33/5614 (2013.01);
Abstract

A method for non-contrast enhanced 4D time resolved dynamic magnetic resonance angiography using arterial spin labeling of blood water as an endogenous tracer and a multiphase balanced steady state free precession readout is presented. Imaging can be accelerated with dynamic golden angle radial acquisitions and k-space weighted imaging contrast (KWIC) image reconstruction and it can be used with parallel imaging techniques. Quantitative tracer kinetic models can be formed allowing cerebral blood volume, cerebral blood flow and mean transit time to be estimated. Vascular compliance can also be assessed using 4D dMRA by synchronizing dMRA acquisitions with the systolic and diastolic phases of the cardiac cycle.


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