The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 2019
Filed:
Sep. 08, 2016
Applicant:
Yeda Research and Development Co. Ltd., Rehovot, IL;
Inventors:
Assignee:
Yeda Research and Development Co. Ltd., Rehovot, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G16B 15/00 (2019.01); C12N 9/18 (2006.01); C12N 9/16 (2006.01); C12N 9/10 (2006.01); G16B 30/00 (2019.01); G16B 35/00 (2019.01); G16C 20/10 (2019.01); G16C 20/60 (2019.01); G16B 15/20 (2019.01);
U.S. Cl.
CPC ...
G16B 15/00 (2019.02); C12N 9/1007 (2013.01); C12N 9/16 (2013.01); C12N 9/18 (2013.01); C12Y 201/01037 (2013.01); C12Y 301/01007 (2013.01); C12Y 301/08001 (2013.01); G16B 15/20 (2019.02); G16B 30/00 (2019.02); G16B 35/00 (2019.02); G16C 20/10 (2019.02); G16C 20/60 (2019.02);
Abstract
A method for designing and selecting a protein having a stabilized structure compared to a corresponding wild type protein, and proteins having at least six amino acid substitutions with respect to a corresponding wild type protein, designed for improved thermal stability, improved specific activity and/or improved expression levels, are provided herein.