The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 05, 2019

Filed:

May. 09, 2018
Applicant:

Warp Drive Bio, Inc., Cambridge, MA (US);

Inventors:

Gregory L. Verdine, Boston, MA (US);

M. James Nichols, Charlestown, MA (US);

Sharon A. Townson, Cambridge, MA (US);

Uddhav Kumar Shigdel, Cambridge, MA (US);

Seung-Joo Lee, Cambridge, MA (US);

Dylan T. Stiles, Chestnut Hill, MA (US);

Neville J. Anthony, Northborough, MA (US);

Assignee:

Revolution Medicines, Inc., Redwood City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); C07K 1/08 (2006.01); C07K 5/083 (2006.01); C07K 7/64 (2006.01); C07K 1/13 (2006.01); C07K 5/02 (2006.01); C12Q 1/533 (2006.01); G01N 33/566 (2006.01); C07K 5/062 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6845 (2013.01); C07K 1/086 (2013.01); C07K 1/13 (2013.01); C07K 5/0215 (2013.01); C07K 5/06034 (2013.01); C07K 5/0808 (2013.01); C07K 7/64 (2013.01); C07K 7/645 (2013.01); C12Q 1/533 (2013.01); G01N 33/566 (2013.01); G01N 2333/82 (2013.01); G01N 2333/90209 (2013.01); G01N 2410/08 (2013.01); G01N 2500/02 (2013.01);
Abstract

The present disclosure provides methods and reagents useful for analyzing protein-protein interfaces such as interfaces between a presenter protein (e.g., a member of the FKBP family, a member of the cyclophilin family, or PIN1) and a target protein. In some embodiments, the target and/or presenter proteins are intracellular proteins. In some embodiments, the target and/or presenter proteins are mammalian proteins.


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