The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 2019
Filed:
Dec. 18, 2017
Applicant:
Stichting Katholieke Universiteit, Nijmegen, NL;
Inventors:
Waander Laurens Van Heerde, Nijmegen, NL;
Richard Hendrik Blaauw, Nijmegen, NL;
Assignee:
STICHTING KATHOLIEKE UNIVERSITEIT, Nijmegan, NL;
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/37 (2006.01); C12Q 1/56 (2006.01); C12Q 1/66 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/37 (2013.01); C12Q 1/56 (2013.01); C12Q 1/66 (2013.01); G01N 2333/745 (2013.01);
Abstract
The present invention relates to a method for in vitro determining generation of a haemostasis factor such as thrombin and/or plasmin in a test sample using a chemiluminescent substrate specific for said blood clotting factor. Upon cleavage of the substrate, a luminescent signal is generated with the aid of a luciferase. The invention also relates to a kit for in vitro determining generation of a haemostasis factor in a test sample, and to novel chemiluminescent substrates for the determination of thrombin and plasmin.