The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 2019
Filed:
Dec. 18, 2017
Sanofi, Paris, FR;
Han Li, Yardley, PA (US);
Dorothea Kominos, Millington, NJ (US);
Jie Zhang, Cambridge, MA (US);
Alla Pritsker, Cambridge, MA (US);
Matthew Davison, Cambridge, MA (US);
Nicolas Baurin, Arpajon, FR;
Govindan Subramanian, Belle Mead, NJ (US);
Xin Chen, Edison, NJ (US);
SANOFI, Paris, FR;
Abstract
The invention provides antibodies that specifically bind to Kallidin or des-Arg10-Kallidin. The invention also provides pharmaceutical compositions, as well as nucleic acids encoding anti-Kallidin or des-Arg10-Kallidin antibodies, recombinant expression vectors and host cells for making such antibodies, or fragments thereof. Methods of using antibodies of the invention to modulate Kallidin or des-Arg10-Kallidin activity or detect Kallidin or des-Arg10-Kallidin or, either in vitro or in vivo, are also provided by the invention. The invention further provides methods of making antibodies that specifically bind to des-Arg-Bradykinin and des-Arg-Kallidin-like peptide.