The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 2019
Filed:
Feb. 22, 2017
Applicant:
Ucb Biopharma Sprl, Brussels, BE;
Inventors:
Teresa De Haro Garcia, Slough, GB;
Martin Alexander Lowe, Slough, GB;
Malcolm Maccoss, Seabrook Island, SC (US);
Richard David Taylor, Slough, GB;
Zhaoning Zhu, Slough, GB;
Assignee:
UCB Biopharma SPRL, Brussels, BE;
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/10 (2006.01); C07D 417/14 (2006.01); A61P 33/06 (2006.01);
U.S. Cl.
CPC ...
C07D 417/10 (2013.01); A61P 33/06 (2018.01); C07D 417/14 (2013.01);
Abstract
A series of 3-imino-5-methyl-1,2,4-thiadiazinane 1,1-dioxide derivatives of formula (I), substituted in the 5-position by a phenyl moiety NH which in turn is meta-substituted by an optionally substituted fused bicyclic heteroaromatic ring system containing at least one nitrogen atom, being selective inhibitors of plasmepsin V activity, are beneficial as pharmaceutical agents, especially in the treatment of malaria.