The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 05, 2019

Filed:

Jun. 03, 2016
Applicant:

Je IL Pharmaceutical Co., Ltd., Seoul, KR;

Inventors:

Hyunho Lee, Gyeonggi-do, KR;

Kwangwoo Chun, Gyeonggi-do, KR;

Bo-Young Joe, Chungcheongbuk-do, KR;

Eun Seon Kim, Gyeonggi-do, KR;

Eun Sung Jang, Gyeonggi-do, KR;

Hyeongchan Oh, Gyeonggi-do, KR;

Jeong-Min Kim, Gyeonggi-do, KR;

Jiseon Park, Gyeonggi-do, KR;

Hanchang Lee, Seoul, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/06 (2006.01); A61K 31/4375 (2006.01); C07D 471/04 (2006.01); A61K 31/497 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
C07D 401/06 (2013.01); A61K 31/4375 (2013.01); A61K 31/497 (2013.01); A61P 25/00 (2018.01); C07D 471/04 (2013.01);
Abstract

The present invention relates to novel tricyclic derivative compounds, and more specifically to tricyclic derivative compounds, optical isomers thereof, racemates thereof, or pharmaceutically acceptable salts thereof, which have excellent activity against PARP-1, tankyrase-1 or tankyrase-2. The tricyclic derivative compounds, optical isomers thereof, racemates thereof or pharmaceutically acceptable salts thereof according to the present invention have inhibitory activity against PARP-1, tankyrase-1, or tankyrase-2, and thus can be effectively used for the prevention or treatment of neuropathic pain, neurodegenerative diseases, cardiovascular diseases, diabetic neuropathy, inflammatory diseases, osteoporosis, or cancer.


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