The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 05, 2019

Filed:

Feb. 21, 2018
Applicants:

Cathay R&d Center Co., Ltd., New District, Shanghai, CN;

Cibt America Inc., Newark, DE (US);

Inventors:

Xiucai Liu, Shanghai, CN;

Charlie Liu, Shanghai, CN;

Bingbing Qin, Shanghai, CN;

Naiqiang Li, Shanghai, CN;

Yang Chen, Shanghai, CN;

Assignees:

CATHAY BIOTECH INC., Shanghai, CN;

CIBT AMERICA INC., Newark, DE (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 209/84 (2006.01); C07C 211/09 (2006.01); B01D 21/26 (2006.01); B01D 3/34 (2006.01); B01D 1/00 (2006.01); B01D 3/40 (2006.01);
U.S. Cl.
CPC ...
C07C 209/84 (2013.01); B01D 1/00 (2013.01); B01D 3/34 (2013.01); B01D 3/40 (2013.01); B01D 21/262 (2013.01); C07C 211/09 (2013.01);
Abstract

The present invention relates to a method for the purification of cadaverine from an aqueous cadaverine salt composition comprising one or more involatile impurities, the method comprising: (1) mixing the aqueous cadaverine salt composition with one or more bases to provide an aqueous cadaverine composition having a pH of at least about 12; (2) distilling or evaporating the aqueous cadaverine composition to produce an aqueous cadaverine solution, wherein one or more solvents are added to the evaporation/distillation system before the evaporation/distillation stops, and the one or more solvents comprise at least one or more high boiling point (HBP) solvents having a boiling point of at least 185° C. (1 atm); and (3) subjecting the aqueous cadaverine solution to one or more rectification steps to provide a cadaverine product.


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