The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 2019
Filed:
Feb. 14, 2014
Applicant:
The Johns Hopkins University, Baltimore, MD (US);
Inventors:
Jonathan Schneck, Baltimore, MD (US);
Christian Schuetz, Baltimore, MD (US);
Assignee:
THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/69 (2017.01); C07K 16/18 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); A61K 47/68 (2017.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 47/6923 (2017.08); A61K 47/6891 (2017.08); C07K 16/18 (2013.01); C07K 16/2833 (2013.01); C07K 16/30 (2013.01); B82Y 5/00 (2013.01); C07K 2317/21 (2013.01); C07K 2319/00 (2013.01); C07K 2319/01 (2013.01); C07K 2319/33 (2013.01);
Abstract
This disclosure describes compositions and methods for selectively recruiting antigen-specific T cells and re-direct them to kill targeted cells, particularly tumor cells. This approach permits selective engagement of specific effector cell populations and, by using nanoparticles, overcomes the geometric limitations associated with previous approaches.