The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 05, 2019

Filed:

Feb. 03, 2016
Applicant:

The University of Liverpool, Liverpool, GB;

Inventors:

Steve Rannard, Liverpool, GB;

Andrew Owen, Liverpool, GB;

James Hobson, Liverpool, GB;

Neill Liptrott, Liverpool, GB;

Pierre Chambon, Liverpool, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 9/16 (2006.01); A61K 47/10 (2017.01); A61K 47/34 (2017.01); A61K 9/107 (2006.01); C08F 220/28 (2006.01); A61K 9/00 (2006.01); A61K 31/513 (2006.01); A61K 31/536 (2006.01); B01F 17/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1641 (2013.01); A61K 9/0053 (2013.01); A61K 9/107 (2013.01); A61K 9/1075 (2013.01); A61K 31/513 (2013.01); A61K 31/536 (2013.01); A61K 47/10 (2013.01); A61K 47/34 (2013.01); B01F 17/0028 (2013.01); C08F 220/28 (2013.01); C08F 2220/286 (2013.01); C08F 2438/01 (2013.01);
Abstract

An oil-in-water emulsion comprises an emulsifier which is a non-gelled branched polymer (e.g. a branched vinyl polymer), wherein the ends of at least some of the chains of said polymer terminate in an alkyl chain of 5 carbon atoms or more, and wherein the oil-in-water emulsion takes the form of particles having a z-average diameter of no greater than about 1000 nm. This is useful in, for example, facilitating the carrying of hydrophobic materials within aqueous systems, to enhance oral drug delivery. The oil-in-water emulsion may be prepared by mixing an oil phase with an aqueous phase in the presence of an emulsifier, wherein said emulsifier is a non-gelled branched polymer, wherein the ends of at least some of the chains of said polymer terminate in an alkyl chain of 5 carbon atoms or more, and wherein the oil-in-water emulsion takes the form of particles having a z-average diameter of no greater than about 1000 nm. The oil phase may comprise a further solvent which is miscible with the oil, said solvent being allowed to evaporate to produce the final emulsion.


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