The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 29, 2019

Filed:

Apr. 28, 2016
Applicant:

Korea University Research and Business Foundation, Seoul, KR;

Inventors:

Sang Jun Sim, Seoul, KR;

So Jin Song, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/553 (2006.01); G01N 21/47 (2006.01); G01N 33/543 (2006.01); G01N 21/552 (2014.01);
U.S. Cl.
CPC ...
G01N 21/47 (2013.01); G01N 21/554 (2013.01); G01N 33/54346 (2013.01); G01N 33/553 (2013.01); G01N 2333/47 (2013.01);
Abstract

A method for screening an anticancer candidate is disclosed. The method includes immobilizing gold nanoparticles onto a substrate; binding a protein involved in carcinogenesis and metastasis to the immobilized gold nanoparticles, recording a spectrum of the protein conjugate, and analyzing the spectrum to obtain reference data; adding a candidate inhibiting the activity of the protein to the protein conjugate, recording a spectrum of the mixture, and analyzing the spectrum to obtain comparative data; and comparing the reference data with the comparative data to determine whether the candidate inhibits the activity of the protein. The method enables screening of a candidate inhibiting the activity of a protein involved in carcinogenesis and metastasis in an accurate and convenient manner.


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