The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2019
Filed:
May. 14, 2015
Applicant:
Stratos Genomics, Inc., Seattle, WA (US);
Inventors:
Robert N. McRuer, Mercer Island, WA (US);
Mark Stamatios Kokoris, Bothell, WA (US);
Assignee:
STRATOS GENOMICS, INC., Seattle, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6825 (2018.01); C12Q 1/6869 (2018.01); G01N 27/447 (2006.01); G01N 33/487 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6825 (2013.01); C12Q 1/6869 (2013.01); G01N 27/44704 (2013.01); G01N 27/44791 (2013.01); G01N 33/48721 (2013.01); C12Q 2565/631 (2013.01);
Abstract
Translocation control for sensing by a nanopore, as well as methods and products related to the same, are provided. Such methods optimize duplex stability to provide high fill rate (of the hybridization sites) but do not prevent rapid dissociation required for high read rates, as well as controlling the translocation of a target molecule for sensing by a nanopore by use of a selective pulsed voltage. Products related to the same include a reporter construct comprising two or more phosphoramidites.