The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 29, 2019

Filed:

Dec. 30, 2014
Applicant:

Chung-ang University Industry-academy Cooperation Foundation, Seoul, KR;

Inventors:

Hyun Ah Kang, Daejeon, KR;

Hye Yun Moon, Seoul, KR;

Hong Jin Kim, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/81 (2006.01); A61K 39/00 (2006.01); C12N 15/70 (2006.01); A61K 9/00 (2006.01); A61K 39/12 (2006.01); C07K 14/005 (2006.01); C12R 1/865 (2006.01);
U.S. Cl.
CPC ...
C12N 15/81 (2013.01); A61K 9/0053 (2013.01); A61K 39/00 (2013.01); A61K 39/12 (2013.01); C07K 14/005 (2013.01); C12N 15/70 (2013.01); A61K 2039/523 (2013.01); A61K 2039/54 (2013.01); C12N 2770/30022 (2013.01); C12N 2770/30034 (2013.01); C12N 2770/30071 (2013.01); C12R 1/865 (2013.01);
Abstract

Disclosed is a gene multiple insertion cassette set including rDNA NTS fragments and an auxotrophic selection marker having an incomplete promoter is developed, and a safe oral recombinant strain having no antibiotic resistant marker is constructed by multiple insertion of an optimum number of the developed gene multiple insertion cassette sets into chromosomes of astrain, a vaccine composition including, as an active ingredient, the above strain, a culture product thereof, a cell lysate, or nodavirus capsid protein (NNVcp) isolated and purified therefrom, and a composition for feed addition including, as an active ingredient, the above strain, a culture product thereof, a cell lysate, or squalene or oxidosqualene isolated and purified therefrom.


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