The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2019
Filed:
Apr. 13, 2018
Applicant:
Arcturus Therapeutics, Inc., San Diego, CA (US);
Inventor:
Jesper Wengel, Odense C, DK;
Assignee:
ARCTURUS THERAPEUTICS, INC., San Diego, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C07H 21/00 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C07H 21/00 (2013.01); C12N 15/111 (2013.01); C12N 2310/14 (2013.01); C12N 2310/31 (2013.01); C12N 2310/321 (2013.01); C12N 2310/323 (2013.01); C12N 2310/3231 (2013.01); C12N 2320/51 (2013.01);
Abstract
This invention provides UNA oligomers for therapeutics having prolonged stability. The UNA oligomers can be composed of one or more 2'-3′-seco-nucleomonomers and one or more natural or non-natural nucleotide monomers. Embodiments include UNA oligomers with phosphorothioate or boranophosphate intermonomer linkages. The UNA oligomers can be used for therapeutics that target oligonucleotides, nucleic acids, or RNAs to reduce their activity.