The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2019
Filed:
Feb. 26, 2016
Applicant:
Fondazione Irccs “istituto Nazionale Dei Tumori”, Milan, IT;
Inventors:
Mario Paolo Colombo, Milan, IT;
Silvia Miotti, Milan, IT;
Elda Tagliabue, Milan, IT;
Sabina Sangaletti, Milan, IT;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/00 (2006.01); C07K 16/46 (2006.01); C07K 16/40 (2006.01); A61K 45/06 (2006.01); C07K 16/30 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); A61K 39/39558 (2013.01); A61K 45/06 (2013.01); C07K 16/30 (2013.01); C12Y 114/11004 (2013.01); A61K 2039/505 (2013.01); C07K 2317/14 (2013.01); C07K 2317/34 (2013.01); C07K 2317/56 (2013.01); C07K 2317/76 (2013.01);
Abstract
The present invention relates to the interaction between JMJD6 protein and collagen and to the possibility of inhibiting this interaction for the prevention and treatment of fibrosis and of tumor metastases. The invention further relates to a compound that is able to block the interaction between collagen and JMJD6 protein, in particular the invention relates to a new monoclonal antibody that recognizes JMJD6 and is able to block this interaction.