The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2019
Filed:
Sep. 24, 2018
Applicant:
Flagship Pioneering Innovations V, Inc., Cambridge, MA (US);
Inventors:
Avak Kahvejian, Lexington, MA (US);
Jordi Mata-Fink, Baltimore, MD (US);
Jonathan Barry Hurov, Bedford, MA (US);
Alexandra Lantermann, Boston, MA (US);
Assignee:
Flagship Pioneering Innovations V, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61P 35/00 (2006.01); C07K 16/30 (2006.01);
U.S. Cl.
CPC ...
C07K 16/303 (2013.01); A61P 35/00 (2018.01); C07K 2317/54 (2013.01); C07K 2317/565 (2013.01); C07K 2317/72 (2013.01); C07K 2317/75 (2013.01); C07K 2319/30 (2013.01);
Abstract
The present invention provides methods for treating cancer using P2RX2 inhibitors, such as P2RX2 inhibitory antibodies, among others. The invention also features compositions containing P2RX2 inhibitors, methods of diagnosing patients with P2RX2-associated cancer, and methods of predicting the response of cancer in a subject to treatment with P2RX2 inhibitors.