The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2019
Filed:
May. 05, 2017
Medimmune, Llc, Gaithersburg, MD (US);
Srinath Kasturirangan, Gaithersburg, MD (US);
Changshou Gao, Gaithersburg, MD (US);
Godfrey Rainey, Gaithersburg, MD (US);
Michelle Morrow, Cambridge, GB;
Claire Louise Dobson, Cambridge, GB;
Stacey Drabic, Gaithersburg, MD (US);
Darren Schofield, Cambridge, GB;
Gianluca Carlesso, Gaithersburg, MD (US);
Kristen Pollizzi, Gaithersburg, MD (US);
Yariv Mazor, Gaithersburg, MD (US);
Michael Oberst, Gaithersburg, MD (US);
Scott A. Hammond, Gaithersburg, MD (US);
Brian Lobo, Gaithersburg, MD (US);
Prakash Manikwar, Gaithersburg, MD (US);
Jonathan Seaman, Cambridge, GB;
Simon Dovedi, Cambridge, GB;
Ronald Herbst, Gaithersburg, MD (US);
MEDIMMUNE, LLC, Gaithersburg, MD (US);
Abstract
The disclosure generally provides proteins that bind two epitopes (e.g., a first and a second epitope) and that are bivalent for binding to each of the first and second epitopes. The disclosure also provides for specific binding proteins, including antibodies, which bind to a target protein. The disclosure also provides compositions comprising such proteins, nucleic acid molecules encoding such proteins and methods of making such proteins. The disclosure provides methods of inducing an immune response in a subject as well as methods for treating or preventing cancer in a subject by administering the proteins, nucleic acid molecules and/or compositions to the subject.