The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 29, 2019

Filed:

Dec. 13, 2018
Applicant:

Bluebird Bio, Inc., Cambridge, MA (US);

Inventors:

Jordan Jarjour, Seattle, WA (US);

Alexander Astrakhan, Seattle, WA (US);

Michael Certo, Medford, MA (US);

Assignee:

bluebird bio, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07H 21/04 (2006.01); C07K 14/00 (2006.01); C07K 16/28 (2006.01); A61K 35/17 (2015.01); A61K 39/00 (2006.01); A61K 45/06 (2006.01); C07K 14/705 (2006.01); C07K 16/40 (2006.01); C12N 9/12 (2006.01); C12N 9/90 (2006.01); C07K 14/725 (2006.01); C07K 14/73 (2006.01); C07K 14/735 (2006.01); C12N 9/06 (2006.01); C12N 9/16 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A61K 35/17 (2013.01); A61K 39/0005 (2013.01); A61K 45/06 (2013.01); C07K 14/7051 (2013.01); C07K 14/7056 (2013.01); C07K 14/70503 (2013.01); C07K 14/70514 (2013.01); C07K 14/70517 (2013.01); C07K 14/70521 (2013.01); C07K 14/70535 (2013.01); C07K 14/70578 (2013.01); C07K 14/70596 (2013.01); C07K 16/2896 (2013.01); C07K 16/40 (2013.01); C12N 9/003 (2013.01); C12N 9/12 (2013.01); C12N 9/16 (2013.01); C12N 9/90 (2013.01); C12N 15/85 (2013.01); C12Y 207/11001 (2013.01); C12Y 502/01008 (2013.01); C07H 21/04 (2013.01); C07K 2317/622 (2013.01); C07K 2319/03 (2013.01); C07K 2319/70 (2013.01); C12N 2510/00 (2013.01);
Abstract

Nucleic acids that encode chemically-inducible fusion proteins, vectors that contain nucleic acids that encode chemically-inducible fusion proteins, chemically-inducible fusion proteins, chemically-inducible fusion protein complexes, and non-natural cells that are modified to express chemically-inducible fusion proteins to spatially and temporally control immune cell signal initiation and downstream responses for treating disease.


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