The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2019
Filed:
Nov. 23, 2016
Applicant:
Alderbio Holdings Llc, Las Vegas, NV (US);
Inventors:
Leon F. Garcia-Martinez, Woodinville, WA (US);
Benjamin H. Dutzar, Seattle, WA (US);
Ethan W. Ojala, Snohomish, WA (US);
Jeffrey T. L. Smith, Bellevue, WA (US);
John A. Latham, Seattle, WA (US);
Assignee:
ALDERBIO HOLDINGS LLC, Las Vegas, NV (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/22 (2006.01); A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 45/06 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C07K 16/2875 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/50 (2013.01); C07K 2317/515 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01);
Abstract
This invention pertains to monovalent agents, including Fab fragments and monovalent monoclonal antibodies analogous to MetMab, having binding specificity to human Nerve Growth Factor ('NGF'), and methods of treating pain in an individual wherein there is no substantial increase in the inflammatory response of the individual following administration of the monovalent agents.