The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 29, 2019

Filed:

Jan. 13, 2017
Applicant:

Jinan University, Guangzhou, Guangdong, CN;

Inventors:

Hao Gao, Guangdong, CN;

Xinsheng Yao, Guangdong, CN;

Rongrong He, Guangdong, CN;

Guodong Chen, Guangdong, CN;

Zhengqun Zhou, Guangdong, CN;

Chuanxi Wang, Guangdong, CN;

Dan Hu, Guangdong, CN;

Hongxia Fan, Guangdong, CN;

Assignee:

Jinan University, Guangzhou, Guangdong, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7016 (2006.01); A61K 31/7034 (2006.01); A61K 31/7052 (2006.01); A61P 25/28 (2006.01); A61P 25/16 (2006.01); C07H 15/24 (2006.01); C07H 1/08 (2006.01); C07H 17/02 (2006.01);
U.S. Cl.
CPC ...
C07H 15/24 (2013.01); A61K 31/7016 (2013.01); A61K 31/7034 (2013.01); A61K 31/7052 (2013.01); A61P 25/16 (2018.01); A61P 25/28 (2018.01); C07H 1/08 (2013.01); C07H 17/02 (2013.01);
Abstract

The present invention relates to dicaffeoyl spermidine cyclized derivatives and a preparation method and use thereof. Biological activity experiments show that the dicaffeoyl spermidine cyclized derivatives of the present invention have anti-Senile dementia activity and antioxidant activity, and their activity are even better than that of a positive control drug, thus suitable for the prevention and treatment of neurodegenerative diseases such as Senile dementia.


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