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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10457700 B1

PDFFull Text
Expired
Date of Patent:
Oct. 29, 2019

Filed:

Mar. 07, 2016

Platinum prodrugs and methods of making and using thereof

Applicant:

University of Georgia Research Foundation, Inc., Athens, GA (US);

Inventors:

Shanta Dhar, Athens, GA (US);

Rakesh Pathak, Athens, GA (US);

Assignee:

UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC., Athens, GA (US);

Attorney:

Meunier Carlin & Curfman LLC

Primary Examiner:

Samira J Jean-Louis

Int. Cl.
CPC ...
A61K 31/282 (2006.01); A61K 9/14 (2006.01); C07F 15/00 (2006.01); A61K 9/51 (2006.01); A61K 9/127 (2006.01); A61K 31/44 (2006.01);
U.S. Cl.
CPC ...
C07F 15/0093 (2013.01); A61K 9/127 (2013.01); A61K 9/14 (2013.01); A61K 9/51 (2013.01); A61K 9/5153 (2013.01); A61K 31/282 (2013.01); A61K 31/44 (2013.01);
Abstract

Disclosed herein are prodrugs of platinum containing anticancer agents such as cisplatin that contain an alkylating moiety. Upon administration, the prodrugs release the platinum containing anticancer agent and the alkylating agent, which can form an adduct with DNA or can protect the platinum containing agent from removal. The disclosed prodrugs can be used to treat various cancers, including cisplatin resistant cancers.

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Dhar, Shanta. (2019). Platinum prodrugs and methods of making and using thereof (U.S. Patent No. 10457700). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10457700

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