The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 29, 2019

Filed:

Aug. 05, 2016
Applicant:

Eisai R&d Management Co., Ltd., Tokyo, JP;

Inventors:

Atsushi Endo, Andover, MA (US);

Robert T. Yu, Arlington, MA (US);

Francis Fang, Andover, MA (US);

Hyeong Wook Choi, Andover, MA (US);

Mingde Shan, Andover, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/00 (2006.01); C07F 9/6561 (2006.01); C07F 9/6558 (2006.01); C07H 21/00 (2006.01); A61K 31/7088 (2006.01);
U.S. Cl.
CPC ...
C07F 9/65616 (2013.01); A61K 31/7088 (2013.01); C07F 9/65583 (2013.01); C07H 21/00 (2013.01);
Abstract

A method of preparation of stereospecific synthesis of diastereomerically pure phosphorodiamidate morpholino oligomers (PMOs) of one of the following general formulas is provided:


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