The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 29, 2019

Filed:

Jun. 03, 2016
Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Jingjun Yin, Green Brook, NJ (US);

Tetsuji Itoh, Somerset, NJ (US);

Jianguo Yin, Plainsboro, NJ (US);

Bangping Xiang, Bridgewater, NJ (US);

Kevin R. Campos, Berkeley Heights, NJ (US);

Alexei Kalinin, Morganville, NJ (US);

Zhuqing Liu, Edison, NJ (US);

Melodie Deniz Christensen, New York, NY (US);

Kevin M. Belyk, Metuchen, NJ (US);

Richard J. Varsolona, Scotch Plains, NJ (US);

Andrew Brunskill, Watchung, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/04 (2006.01); C07D 403/04 (2006.01); C07F 5/02 (2006.01); B01J 31/04 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); B01J 31/04 (2013.01); C07D 403/04 (2013.01); C07F 5/025 (2013.01);
Abstract

The present invention is directed to processes for preparing Substituted Tetracyclic Heterocycle Compounds of formula (I): (I) which may be useful as HCV NS5A inhibitors. The present invention is also directed to compounds that may be useful as synthetic intermediates and catalysts in the processes of the invention.


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