The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2019
Filed:
Oct. 13, 2016
Institut National DE LA Sante ET DE LA Recherche Medicale (Inserm), Paris, FR;
Centre National DE LA Recherche Scientifique (Cnrs), Paris, FR;
Sorbonne Universite, Paris, FR;
Universite Claude Bernard Lyon 1, Villeurbanne, FR;
Marie-Thérèse Dimanche-Boitrel, Melesse, FR;
Stéphane Bach, Sibiril, FR;
Claire Delehouze, La Roche Maurice, FR;
Peter Goekjian, Villeurbanne, FR;
Arnaud Comte, Lyons, FR;
Institut National de la Sante et de la Recherche Medicale (INSERM), Paris, FR;
Centre National de la Recherche Scientifique (CNRS), Paris, FR;
Sorbonne Universite, Paris, FR;
Universite Claude Bernard Lyon 1, Villeurbanne, FR;
Abstract
The present invention relates to new N- and N-substituted sibiriline derivatives of the following general formula (I): (I) or a pharmaceutically acceptable salt and/or solvate thereof, notably for use as drug, in particular for use as inhibitor of cellular necroptosis. The present invention also relates to a pharmaceutical composition comprising such a compound and processes to prepare such a compound. The present invention also encompasses the use of a compound of the general formula (I) for organs preservation.