The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2019
Filed:
May. 08, 2018
Applicant:
Novartis Ag, Basel, CH;
Inventors:
Assignee:
Novartis AG, Basel, CH;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 405/12 (2006.01); C07D 403/12 (2006.01); A61K 31/505 (2006.01); A61K 31/506 (2006.01); C07D 239/47 (2006.01); C07D 401/14 (2006.01); C07D 401/10 (2006.01); C07D 401/12 (2006.01); A61P 29/00 (2006.01); A61P 35/02 (2006.01);
U.S. Cl.
CPC ...
C07D 239/47 (2013.01); A61K 31/505 (2013.01); A61K 31/506 (2013.01); A61P 29/00 (2018.01); A61P 35/02 (2018.01); C07D 401/10 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01);
Abstract
The present invention describes new amino pyrimidine derivatives and pharmaceutically acceptable salts thereof which appear to interact with Bruton's tyrosine kinase (Btk). Accordingly, the novel amino pyrimidines may be effective in the treatment of autoimmune disorders, inflammatory diseases, allergic diseases, airway diseases, such as asthma and chronic obstructive pulmonary disease (COPD), transplant rejection, cancers e.g. of hematopoietic origin or solid tumors.