The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2019
Filed:
May. 12, 2017
Applicant:
Arbutus Biopharma Corporation, Burnaby, CA;
Inventors:
Muthiah Manoharan, Cambridge, MA (US);
Kallanthottathil G. Rajeev, Cambridge, MA (US);
Muthusamy Jayaraman, Cambridge, MA (US);
David Butler, Medford, MA (US);
Michael E. Jung, Cambridge, MA (US);
Assignee:
Arbutus Biopharma Corporation, Burnaby, BC, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/22 (2006.01); A61K 9/127 (2006.01); C07D 295/13 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 47/22 (2013.01); A61K 9/1272 (2013.01); C07D 295/13 (2013.01); C12N 15/113 (2013.01); C12N 15/1137 (2013.01); C12N 2310/14 (2013.01); Y02A 50/463 (2018.01);
Abstract
Disclosed herein are lipid compositions comprising a cationic lipid of formula (I), a neutral lipid, a sterol and a PEG or PEG-modified lipid, wherein formula (I) is Also disclosed are methods of producing the cationic lipid of formula (I).