The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2019
Filed:
Oct. 27, 2017
Applicant:
Variation Biotechnologies Inc., Ottawa, CA;
Inventors:
David E. Anderson, Boston, MA (US);
Anne-Catherine Fluckiger, Saint Genis les Ollières, FR;
Assignee:
Variation Biotechnologies Inc., Ontario, CA;
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); C12N 7/00 (2006.01); C07K 14/005 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); C07K 14/005 (2013.01); C12N 7/00 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/5258 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/57 (2013.01); A61K 2039/575 (2013.01); A61K 2039/70 (2013.01); C07K 2319/40 (2013.01); C12N 2740/13022 (2013.01); C12N 2740/13023 (2013.01); C12N 2740/13034 (2013.01); C12N 2770/24122 (2013.01); C12N 2770/24123 (2013.01); C12N 2770/24134 (2013.01); Y02A 50/392 (2018.01);
Abstract
The present disclosure provides compositions and methods useful for preventing and treating Zika virus infection. As described herein, the compositions and methods are based on development of immunogenic compositions that include virus-like particles (VLPs) which comprise one or more Moloney Murine leukemia virus (MMLV) core proteins and include one or more Zika epitopes, such as, for example, from Zika envelope glycoprotein E and the Zika structural protein NS1 including variants thereof.