The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 29, 2019

Filed:

Mar. 14, 2016
Applicants:

Indiana University Research and Technology Corporation, Indianapolis, IN (US);

Rita Maria Cunha DE Almeida, Porto Alegre, BR;

United States Government As Represented BY the Department of Veterans Affairs, Washington, DC (US);

Inventors:

Robert Bacallao, Indianapolis, IN (US);

James A. Glazier, Bloomington, IN (US);

Sherry G. Clendenon, Indianapolis, IN (US);

Rita Maria Cunha De Almeida, Porto Alegre, BR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4985 (2006.01); C12Q 1/44 (2006.01); G01N 33/68 (2006.01); A61K 31/53 (2006.01); C12Q 1/6883 (2018.01); A61K 31/519 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/53 (2013.01); A61K 31/4985 (2013.01); A61K 31/519 (2013.01); A61K 45/06 (2013.01); C12Q 1/44 (2013.01); C12Q 1/6883 (2013.01); G01N 33/6893 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/916 (2013.01); G01N 2800/347 (2013.01);
Abstract

Described herein is the identification of cGMP-specific phosphodiesterase upregulation in cystic kidney diseases. Also described is the use of cGMP-specific phosphodiesterase inhibitors for preventing the progression and/or treatment of cystic kidney diseases. Other aspects described provide medicaments for preventing the progression and/or treating cystic kidney diseases, and methods of diagnosing cystic kidney disease.


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