The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 29, 2019

Filed:

Jul. 03, 2017
Applicant:

Ension, Inc., Pittsburgh, PA (US);

Inventors:

Ali Hussain, Cape Coral, FL (US);

Linda Cahalan, Cape Coral, FL (US);

Greg Johnson, Pittsburgh, PA (US);

Mark Gartner, Wexford, PA (US);

Patrick Cahalan, Cape Coral, FL (US);

Brian J Fill, Pittsburgh, PA (US);

Jeffrey W. Speakman, Saxonburg, PA (US);

Assignee:

ENSION INC., Pittsburgh, PA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61C 15/04 (2006.01); A61B 17/06 (2006.01); A61B 17/064 (2006.01); A61L 31/04 (2006.01); A61L 31/10 (2006.01); A61L 33/00 (2006.01); B05D 3/06 (2006.01); A61M 1/16 (2006.01); B05D 7/02 (2006.01); B05D 1/36 (2006.01); B05D 1/00 (2006.01);
U.S. Cl.
CPC ...
A61C 15/041 (2013.01); A61B 17/064 (2013.01); A61B 17/06166 (2013.01); A61L 31/048 (2013.01); A61L 31/10 (2013.01); A61L 33/0029 (2013.01); A61B 17/06 (2013.01); A61L 2400/18 (2013.01); A61M 1/1698 (2013.01); B05D 1/36 (2013.01); B05D 1/62 (2013.01); B05D 3/06 (2013.01); B05D 7/02 (2013.01); B05D 2256/00 (2013.01); B05D 2258/00 (2013.01);
Abstract

A method of treating a tubular medical device with a biomolecule comprises the steps of: a) providing a polyolefin tubular substrate forming a tubular medical device; b) cleaning the tubular polyolefin substrate; c) exposing the tubular polyolefin substrate to a reactive gas containing at least one of acrylic acid and siloxane and to plasma energy to yield a plasma-deposited coating on at least one surface of the tubular polyolefin substrate; and d) attaching a biomolecule to the polyolefin substrate following formation of the plasma-deposited coating on at least one surface of the tubular polyolefin substrate, and wherein the biomolecule is at least one of an antibacterial agent, antimicrobial agent, anticoagulant, heparin, antithrombotic agent, platelet agent, anti-inflammatory, enzyme, catalyst, hormone, growth factor, drug, vitamin, antibody, antigen, protein, nucleic acid, dye, a DNA segment, an RNA segment, protein, and peptide.


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