The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2019
Filed:
Sep. 29, 2015
Applicant:
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
Mien-Chie Hung, Houston, TX (US);
Yi Du, Houston, TX (US);
Assignee:
Board of Regents, The University of Texas System, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); A61K 45/06 (2006.01); A61K 31/4184 (2006.01); A61K 31/4425 (2006.01); A61K 31/444 (2006.01); A61K 31/5377 (2006.01); A61K 35/28 (2015.01); B01L 3/00 (2006.01); C12M 1/32 (2006.01); C12M 1/26 (2006.01); C12M 1/34 (2006.01); C12M 1/00 (2006.01); C12N 5/00 (2006.01); C12N 5/079 (2010.01); C12N 5/0775 (2010.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5029 (2013.01); A61K 31/4184 (2013.01); A61K 31/444 (2013.01); A61K 31/4425 (2013.01); A61K 31/5377 (2013.01); A61K 35/28 (2013.01); A61K 45/06 (2013.01); B01L 3/502761 (2013.01); C12M 23/12 (2013.01); C12M 33/14 (2013.01); C12M 41/46 (2013.01); C12M 47/04 (2013.01); C12N 5/0068 (2013.01); C12N 5/0087 (2013.01); C12N 5/0622 (2013.01); C12N 5/0662 (2013.01); G01N 33/56966 (2013.01); C12N 2500/00 (2013.01);
Abstract
Provided herein are methods for identifying and treating cancers that are resistant to PARP inhibition. Methods for sensitizing cancers to a PARP inhibitor therapy are also provided. In some aspects. PARP inhibitor cancers are treated with a PARP inhibitor therapy in combination with a c-Met inhibitor therapy.