The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2019
Filed:
Nov. 28, 2014
Applicant:
Horizon Genomics Gmbh, Vienna, AT;
Inventor:
Tilmann Buerckstuemmer, Vienna, AT;
Assignee:
Horizon Discovery Limited, Cambridge, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/90 (2006.01); C12N 5/071 (2010.01); C12Q 1/6813 (2018.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01); C12N 5/0602 (2013.01); C12N 15/902 (2013.01); C12Q 1/6813 (2013.01); C12N 2800/30 (2013.01);
Abstract
The invention provides for a somatic fully haploid, karyotypically stable human cell line, e.g. obtainable by targeted deletion of one or more disomic chromosomal regions of a somatic near-haploid human parental cell, a method of producing the same, as well as the use of the cell line for producing isogenic cell variants, comprising genomic mutations at different genomic target sites, and a library of such cell variants.