The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 22, 2019

Filed:

Sep. 15, 2017
Applicant:

Roche Innovation Center Copenhagen A/s, Basel, CH;

Inventors:

Susanna Obad, Malmo, SE;

Sakari Kauppinen, Smorum, DK;

Joacim Elmen, Malmo, SE;

Morten Lindow, Copenhagen SV, DK;

Markus Heidenblad, Lund, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 15/11 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/113 (2010.01); A61K 31/713 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 31/713 (2013.01); A61K 45/06 (2013.01); C12N 15/111 (2013.01); C12N 15/1131 (2013.01); C12N 2310/113 (2013.01); C12N 2310/14 (2013.01); C12N 2310/141 (2013.01); C12N 2310/315 (2013.01); C12N 2310/32 (2013.01); C12N 2310/321 (2013.01); C12N 2310/322 (2013.01); C12N 2310/3231 (2013.01); C12N 2310/3341 (2013.01); C12N 2310/34 (2013.01); C12N 2310/351 (2013.01); C12N 2310/3513 (2013.01); C12N 2310/3525 (2013.01); C12N 2310/3533 (2013.01); C12N 2320/31 (2013.01); Y02A 50/465 (2018.01);
Abstract

The present invention relates to very short heavily modified oligonucleotides which target and inhibit microRNAs in vivo, and their use in medicaments and pharmaceutical compositions.


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