The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 22, 2019

Filed:

Aug. 16, 2017
Applicants:

Neurimmune Holding Ag, Schlieren, CH;

University of Zurich, Zurich, CH;

Inventors:

Jan Grimm, Dübendorf, CH;

Roland Martin, Zurich, CH;

Benoit Combaluzier, Urdorf, CH;

Ivan Jelcic, Zurich, CH;

Assignees:

Neurimmune Holding AG, Schlieren, CH;

University of Zurich, Zurich, CH;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/42 (2006.01); A61K 45/06 (2006.01); C07K 14/005 (2006.01); C12N 7/00 (2006.01); C07K 16/08 (2006.01); G01N 33/569 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/084 (2013.01); A61K 39/42 (2013.01); A61K 45/06 (2013.01); C07K 14/005 (2013.01); C07K 16/081 (2013.01); C12N 7/00 (2013.01); G01N 33/56983 (2013.01); G01N 33/6893 (2013.01); C07K 2317/21 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01); C12N 2710/22022 (2013.01); G01N 2333/025 (2013.01);
Abstract

Provided are novel human-derived antibodies specifically recognizing polyomavirus polypeptides, preferably capable of binding to polyomaviruses of the type of JC virus (JCV) and/or BK virus (BKV) as well as methods related thereto. Furthermore, assays and kits related to antibodies specific for polyomaviruses, polyomavirus VP1 and or polyomavirus VP1 Virus-Like Particles (VLPs), preferably of the type of JCV and/or BKV, are disclosed. The human-derived antibodies as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for polyomavirus targeted immunotherapy and diagnostics.


Find Patent Forward Citations

Loading…