The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2019
Filed:
Jul. 16, 2015
Applicant:
Institute of Biotechnology Academy of Military Medical Sciences P.l.a. China, Beijing, CN;
Inventors:
Wei Chen, Beijing, CN;
Xiaopeng Zhang, Beijing, CN;
Changming Yu, Beijing, CN;
Ling Fu, Beijing, CN;
Mengmeng Dai, Beijing, CN;
Jun Zhang, Beijing, CN;
Junjie Xu, Beijing, CN;
Lihua Hou, Beijing, CN;
Jianmin Li, Beijing, CN;
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/49 (2006.01); A61K 38/18 (2006.01); C07K 1/16 (2006.01); C07K 1/18 (2006.01); C07K 1/20 (2006.01); C07K 16/22 (2006.01); C07K 19/00 (2006.01); C12N 5/10 (2006.01); C12N 15/63 (2006.01); B01D 15/20 (2006.01); B01D 15/32 (2006.01); B01D 15/34 (2006.01); B01D 15/36 (2006.01); B01D 15/42 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/49 (2013.01); A61K 38/18 (2013.01); B01D 15/203 (2013.01); B01D 15/327 (2013.01); B01D 15/34 (2013.01); B01D 15/361 (2013.01); B01D 15/426 (2013.01); C07K 1/16 (2013.01); C07K 1/18 (2013.01); C07K 1/20 (2013.01); C07K 16/22 (2013.01); C07K 19/00 (2013.01); C12N 5/10 (2013.01); C12N 15/63 (2013.01); A61K 38/00 (2013.01);
Abstract
Provided are a platelet-derived growth factor B derivative, the encoding nucleic acid molecule thereof, and a vector and host cell having the nucleic acid molecule. Also provided are a preparation method for the mutant, and the use of the mutant in preparing medications for promoting cell division, cell proliferation, wound healing, skin regeneration, bone and tooth defect regeneration, and joint repair.