The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2019
Filed:
Feb. 16, 2017
Applicant:
Monopar Therapeutics Inc., Wilmette, IL (US);
Inventors:
Richard Olson, Birmingham, AL (US);
Gerald Walsh, Birmingham, AL (US);
Assignee:
MONOPAR THERAPEUTICS INC., Northbrook, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 15/24 (2006.01); C07H 15/252 (2006.01); C07H 19/04 (2006.01); A61K 31/704 (2006.01);
U.S. Cl.
CPC ...
C07H 15/252 (2013.01); A61K 31/704 (2013.01); C07H 15/24 (2013.01); C07H 19/04 (2013.01);
Abstract
2-pyrrolino-13-deoxyanthracycline derivatives, medical uses thereof, and a process for making them. A 2-pyrrolino-13-deoxyanthracycline and a 13-deoxyanthracycline can be administered to a patient simultaneously or sequentially in amounts to produce a synergistic therapeutic effect with increased potency and efficacy, compared to the sum of the effects of each drug when administered alone. A composition or preparation of a 2-pyrrolino-13-deoxyanthracycline and a 13-deoxyanthracycline for producing a potent anticancer therapeutic effect is also provided.