The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2019
Filed:
May. 04, 2015
Los Alamos National Security, Llc, Los Alamos, NM (US);
Justin Wilson, Los Alamos, NM (US);
Eva Birnbaum, Los Alamos, NM (US);
Kevin John, Santa Fe, NM (US);
Francois Nortier, Los Alamos, NM (US);
Michael Fassbender, Los Alamos, NM (US);
Valery Radchenko, Los Alamos, NM (US);
Jonathan Ward Engle, Los Alamos, NM (US);
Triad National Security, LLC, Los Alamos, NM (US);
Abstract
Selective chelation of bismuth radionuclide ions from a mixture including actinium radionuclide ions involves exposing a ligand to an aqueous solution that includes bismuth radionuclide ions and actinium radionuclide ions under conditions whereby the bismuth radionuclide ions selectively chelate to the ligand for form cationic complexes of the bismuth radionuclide ions. and separating the cationic complexes of the bismuth radionuclide ions from the actinium radionuclide ions. The ligands have a structure based on a 12-membered cyclen ring and may include pendant functional groups that can be derivatized with biological targeting vectors for targeted alpha therapy.