The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2019
Filed:
Dec. 08, 2016
Ucb Biopharma Sprl, Brussels, BE;
Katholieke Universiteit Leuven, Leuven, BE;
Helen Tracey Horsley, Slough, GB;
Richard John Mears, Abingdon, GB;
Judi Charlotte Neuss, Slough, GB;
James Thomas Reuberson, Slough, GB;
UCB Biopharma SPRL, Brussels, BE;
Katholieke Universiteit Leuven, K.U.Leuven R&D, Leuven, BE;
Abstract
A series of 1,2,6,7,9,9a-hexahydropyrazino[1,2-d][1,2,4]triazin-4-one derivatives, substituted in the 8-position by an optionally substituted fused bicyclic heteroaromatic group, and in the 3-position by a range of functional groups, being selective inhibitors of phosphatidylinositol-4-kinase IIIβ (PI4KIIIβ) activity, are beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders; viral diseases and malaria; and organ and cell transplant rejection.