The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2019
Filed:
Jun. 08, 2016
Applicant:
University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Inventors:
Peter Wipf, Pittsburgh, PA (US);
Bennett Van Houten, Pittsburgh, PA (US);
Wei Qian, Pittsburgh, PA (US);
Chaemin Lim, Pittsburgh, PA (US);
Assignee:
University of Pittsburgh—Of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/352 (2006.01); C07D 311/92 (2006.01); A61K 45/06 (2006.01); A61P 25/28 (2006.01); A61P 35/00 (2006.01); C07D 405/12 (2006.01);
U.S. Cl.
CPC ...
C07D 311/92 (2013.01); A61K 45/06 (2013.01); A61P 25/28 (2018.01); A61P 35/00 (2018.01); C07D 405/12 (2013.01);
Abstract
Provided herein are compounds having the general formula compositions, and methods useful for treating cancer and neurodegeneration. The compounds comprise a mitochondria-targeting moiety linked to β-lapachone or a β-lapachone derivative.