The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2019
Filed:
Jul. 25, 2014
Applicant:
Janssen Sciences Ireland Uc, Co Cork, IE;
Inventors:
Koen VanDyck, Paal-Beringen, BE;
Bart Rudolf Romanie Kesteleyn, Berlare, BE;
Serge Maria Aloysius Pieters, Hulst, NL;
Geert Rombouts, Borsbeek, BE;
Wim Gaston Verschueren, Berchem, BE;
Pierre Jean-Marie Bernard Raboisson, Rosieres, BE;
Assignee:
Janssen Sciences Ireland UC, Little Island, Co Cork, IE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 207/34 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01); A61K 31/40 (2006.01); A61K 31/4025 (2006.01); A61K 31/454 (2006.01); A61P 31/00 (2006.01);
U.S. Cl.
CPC ...
C07D 207/34 (2013.01); A61K 31/40 (2013.01); A61K 31/4025 (2013.01); A61K 31/454 (2013.01); A61P 31/00 (2018.01); C07D 401/12 (2013.01); C07D 405/12 (2013.01);
Abstract
Inhibitors of HBV replication of Formula (IA) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein X and Rto Rhave the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.