The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 22, 2019

Filed:

Nov. 05, 2012
Applicant:

Agency for Science, Technology and Research, Singapore, SG;

Inventors:

Charlotte Hauser, Singapore, SG;

Yihua Loo, Singapore, SG;

Andrew C. A. Wan, Singapore, SG;

Michael Reithofer, Singapore, SG;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/36 (2006.01); A61K 31/7088 (2006.01); A61K 35/28 (2015.01); A61K 35/51 (2015.01); A61K 35/545 (2015.01); A61K 38/06 (2006.01); A61K 38/07 (2006.01); A61K 38/08 (2019.01); A61K 38/18 (2006.01); A61K 38/19 (2006.01); A61K 47/18 (2017.01); A61L 26/00 (2006.01); A61L 27/26 (2006.01); A61L 27/38 (2006.01); A61L 27/48 (2006.01); A61L 27/52 (2006.01); A61L 27/54 (2006.01); C08L 5/00 (2006.01); C08L 5/04 (2006.01); C08L 5/08 (2006.01); C08L 5/10 (2006.01); C08L 5/16 (2006.01); C08L 71/02 (2006.01); C08L 89/00 (2006.01); C12N 5/00 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 47/36 (2013.01); A61K 31/7088 (2013.01); A61K 35/28 (2013.01); A61K 35/51 (2013.01); A61K 35/545 (2013.01); A61K 38/06 (2013.01); A61K 38/07 (2013.01); A61K 38/08 (2013.01); A61K 38/18 (2013.01); A61K 38/1825 (2013.01); A61K 38/19 (2013.01); A61K 47/183 (2013.01); A61L 26/008 (2013.01); A61L 26/0052 (2013.01); A61L 26/0066 (2013.01); A61L 26/0095 (2013.01); A61L 27/26 (2013.01); A61L 27/3834 (2013.01); A61L 27/48 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); C08L 5/00 (2013.01); C08L 5/04 (2013.01); C08L 5/08 (2013.01); C08L 5/10 (2013.01); C08L 5/16 (2013.01); C08L 71/02 (2013.01); C08L 89/00 (2013.01); C12N 5/0068 (2013.01); C12N 15/113 (2013.01); C12N 2310/11 (2013.01); C12N 2320/32 (2013.01); C12N 2533/30 (2013.01); C12N 2533/50 (2013.01); C12N 2533/72 (2013.01);
Abstract

The present invention relates to composite hydrogels comprising at least one non-peptidic polymer and at least one peptide having the general formula: Z—(X)—(Y)—Z', wherein Z is an N-terminal protecting group; X is, at each occurrence, independently selected from an aliphatic amino acid, an aliphatic amino acid derivative and a glycine; Y is, at each occurrence, independently selected from a polar amino acid and a polar amino acid derivative; Z′ is a C-terminal protecting group; m is an integer selected from 2 to 6; n is selected from 1 or 2; and p is selected from 0 or 1. The present invention further relates to methods of producing the composite hydrogels, to uses of the composite hydrogels for the delivery of drugs and other bioactive agents/moieties, as an implant or injectable agent that facilitates tissue regeneration, and as a topical agent for wound healing. The present invention further relates to devices and pharmaceutical or cosmetic compositions comprising the composite hydrogels and to medical uses of the composite hydrogels.


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