The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2019
Filed:
Jul. 31, 2015
Applicant:
Akeso Biopharma, Inc., Zhongshan, CN;
Inventors:
Baiyong Li, Zhongshan, CN;
Yu Xia, Zhongshan, CN;
Zhongmin Wang, Zhongshan, CN;
Peng Zhang, Zhongshan, CN;
Xinghua Pang, Zhongshan, CN;
Assignee:
AKESO BIOPHARMA, INC., Zhongshan, Guangdong, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 49/00 (2006.01); A61K 39/00 (2006.01); C07K 16/28 (2006.01); C07K 19/00 (2006.01); C12N 5/10 (2006.01); C12N 15/63 (2006.01); G01N 33/577 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39541 (2013.01); A61K 39/395 (2013.01); C07K 16/28 (2013.01); C07K 16/2896 (2013.01); C07K 19/00 (2013.01); C12N 5/10 (2013.01); C12N 15/63 (2013.01); G01N 33/577 (2013.01);
Abstract
The present invention belongs to the fields of tumor therapy and molecular immunology, and provides an anti-CTLA4 monoclonal antibody or antigen binding fragment thereof, a pharmaceutical composition thereof and use thereof. The monoclonal antibody of the present invention can block the binding of CTLA4 to B7, relieve the immunosuppression on the body by CTLA4, and activate T lymphocytes.