The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2019
Filed:
Oct. 07, 2014
Hospices Civils DE Lyon, Lyons, FR;
The Regents of the University of California, Oakland, CA (US);
Universite Claude Bernard-lyon 1, Villeurbanne, FR;
Institut D'enseignement Superieur ET DE Recherche En Alimentation, Sante Animale, Sciences Agronomiques ET DE L'environnement, Marcy l'etoile, FR;
Institut National DE LA Sante ET DE LA Recherche Medicale (Inserm), Paris, FR;
Hospices Civils de Lyon, Lyons, FR;
The Regents of the University of California, Oakland, CA (US);
Universite Claude-Bernard-Lyon 1, Villeurbanne, FR;
Institut D'Enseignement Superieur et de Recherche en Alimentation, Sante Animale, Sciences Argonomiques et de l'Environnement, Marcy l'Etoile, FR;
Institut National de la Sante et de la Recherche Medicale, Paris, FR;
Abstract
The present invention relates to a viral vector for expression of the cell death-inducing PUMA protein, for use in gene therapy, for example for the treatment of rheumatoid arthritis. This vector consists in particular of a recombinant adenovirus expressing the gene encoding the PUMA protein and of a recombinant baculovirus containing a coxsackie-adenovirus receptor (CAR).